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Case report of neurofibromatosis type 1 combined with primary ciliary dyskinesia

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 933-937 doi: 10.1007/s11684-021-0860-7

Abstract: Neurofibromatosis (NF) is a genetic disease in which the lungs are rarely involved.Herein, we report a patient diagnosed with NF on the basis of the results of genetic testing who presented

Keywords： primary ciliary dyskinesia     neurofibromatosis     bronchiectasis     transmission electron microscopy     geneticsequencing    

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Exome sequencing greatly expedites the progressive research of Mendelian diseases

Xuejun Zhang

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 42-57 doi: 10.1007/s11684-014-0303-9

Abstract:

The advent of whole-exome sequencing (WES) has facilitated the discovery of rare structure and functionalgenetic variants.Combining exome sequencing with linkage studies is one of the most efficient strategies in searchingWe illustrate the workflow of exome capture and sequencing to highlight the advantages of WES.

Keywords： genetics     whole-exome sequencing     Mendelian disease     disease gene    

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Accurate quantification of 3′-terminal 2′-O-methylated small RNAs by utilizing oxidative deep sequencing

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 240-250 doi: 10.1007/s11684-021-0909-7

Abstract: , we profiled 3′-terminal 2′-O-methyl plant miRNAs in the livers of rice-fed mice by oxidative deep sequencing

Keywords： small RNAs     2′-O-methylation     sequencing     RT-qPCR    

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TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways

Daniel Wai-Hung Ho,Alan Ka-Lun Kai,Irene Oi-Lin Ng

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 322-330 doi: 10.1007/s11684-015-0408-9

Abstract:

This study systematically evaluates the TCGA whole-transcriptome sequencing data of hepatocellular

Keywords： TCGA     whole-transcriptome sequencing     HCC     liver cancer    

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Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing

Frontiers of Medicine   Pages 889-906 doi: 10.1007/s11684-023-0994-x

Abstract: This study aimed to depict the genetic landscape of Chinese PCNSLs.Whole-genome sequencing was performed on 68 newly diagnosed Chinese PCNSL samples, whose genomic characteristicsgenomic landscape of newly diagnosed Chinese PCNSLs, thereby enriching the present understanding of the genetic

Keywords： primary central nervous system lymphoma     whole-genome sequencing     TMSB4X     copy number variation    

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Machine learning modeling identifies hypertrophic cardiomyopathy subtypes with genetic signature

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 768-780 doi: 10.1007/s11684-023-0982-1

Abstract: by using machine learning modeling and interactome network detection techniques based on whole-exome sequencingBy employing echocardiography and genetic screening for the 46 genes, HCM can be classified into two

Keywords： machine learning methods     hypertrophic cardiomyopathy     genetic risk    

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Exploring the cancer genome in the era of next-generation sequencing

Hui Dong, Shengyue Wang

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 48-55 doi: 10.1007/s11684-012-0182-x

Abstract:

The emergence of next-generation sequencing technologies has led to dramatic advances in cancer genomeThe increased efficiency and resolution of next-generation sequencing greatly facilitate the detectionof genetic, genomic, and epigenomic alterations, such as single nucleotide mutations, small insertionsComprehensive analysis of cancer genomes through approaches of whole genome, exome, and transcriptome sequencingThe present study briefly reviews the recent pioneering studies on cancer genome sequencing and provides

Keywords： next-generation sequencing     cancer genome     whole genome sequencing     exome     transcriptome    

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Comparative study on microbial community in intermittently aerated sequencing batch reactors (SBR) and

Xiaolin Sheng, Rui Liu, Xiaoyan Song, Lujun Chen, Kawagishi Tomoki

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 3, doi: 10.1007/s11783-017-0929-3

Abstract: A traditional sequencing batch reactor (SBR) and two intermittently aerated sequencing batch reactors

Keywords： wastewater     Intermittent aeration     Microbial community     Partial nitrification–denitrification process     Sequencing    

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Simultaneous denitrifying phosphorus accumulation in a sequencing batch reactor

YUAN Linjiang, HAN Wei, WANG Lei, YANG Yongzhe, WANG Zhiying

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 1,   Pages 23-27 doi: 10.1007/s11783-007-0004-6

Abstract: treatment process, denitrifying phosphorus accumulation (DNPA) and its affecting factors were studied in a sequencing

Keywords： SBR     synthetic wastewater     Induced DNPA     resource     removal ability    

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Improvement of nitrification efficiency by bioaugmentation in sequencing batch reactors at low temperature

Di CUI,Ang LI,Tian QIU,Rui CAI,Changlong PANG,Jihua WANG,Jixian YANG,Fang MA,Nanqi REN

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 6,   Pages 937-944 doi: 10.1007/s11783-014-0668-7

Abstract: Bioaugmentation is an effective method of treating municipal wastewater with high ammonia concentration in sequencing

Keywords： nitrification     sequencing batch reactors (SBRs)     bioaugmentation     low temperature    

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Interplay between diet and genetic susceptibility in obesity and related traits

Tiange Wang, Min Xu, Yufang Bi, Guang Ning

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 601-607 doi: 10.1007/s11684-018-0648-6

Abstract: Longitudinal studies and randomized intervention trials have shown that genetic susceptibility to obesity

Keywords： diet     genetic susceptibility     obesity     interaction    

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Effects of La, Ce on nitrogen removal in sequencing batch reactor

Qing XIA , Rui LIANG , Yuning HONG , Lili DING , Hongqiang REN , Yuxiang MAO , Mingyu ZHAO ,

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 3,   Pages 369-374 doi: 10.1007/s11783-009-0036-1

Abstract: short-term biological effects of rare earth ions (La, Ce) and their mixture on the nitrogen removal in a sequencing

Keywords： rare earth     La3+     Ce3+     inorganic nitrogen     nitrogen removal     sequencing batch reactor    

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Optimal design of steel skeletal structures using the enhanced genetic algorithm methodology

Tugrul TALASLIOGLU

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 4,   Pages 863-889 doi: 10.1007/s11709-019-0523-9

Abstract: For this purpose, the enhanced genetic algorithm methodology named EGAwMP is utilized as an optimizationThe evolutionary search mechanism of EGAwMP is constituted on the basis of generational genetic algorithminto sub-populations and using of a radial basis neural network for dynamically adjustment of EGAwMP’s genetic

Keywords： design optimization     genetic algorithm     multiple populations     neural network    

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METAGENOMICS COMBINED WITH HIGH-THROUGHPUT SEQUENCING REVEALS THE METHANOGENIC POTENTIAL OF FRESH CORN

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 3,   Pages 403-423 doi: 10.15302/J-FASE-2022471

Abstract:

● Methane production from fresh straw was 7.50% higher than dry straw.

Keywords： fresh corn straw     high solid anaerobic digestion     metagenomics     microbial communities     thermophilic    

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Research progress on genetic improvement of

Chuanping YANG

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 4,   Pages 391-401 doi: 10.15302/J-FASE-2017183

Abstract: Over the past 30 years, effective progress has been made in genetic improvement and molecular breedingcrossbreeding and asexual propagation techniques, ploidy breeding and mutation breeding technology, genome sequencingmolecular markers were developed and the high density genetic map constructed.All this research has provided a model and data for the foundation of forest genetic improvement and

Keywords： Betula platyphylla     genetic improvement     molecular breeding     seed orchard    

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Title Author Date Type Operation

Case report of neurofibromatosis type 1 combined with primary ciliary dyskinesia

Journal Article

Exome sequencing greatly expedites the progressive research of Mendelian diseases

Xuejun Zhang

Journal Article

Accurate quantification of 3′-terminal 2′-O-methylated small RNAs by utilizing oxidative deep sequencing

Journal Article

TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways

Daniel Wai-Hung Ho,Alan Ka-Lun Kai,Irene Oi-Lin Ng

Journal Article

Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing

Journal Article

Machine learning modeling identifies hypertrophic cardiomyopathy subtypes with genetic signature

Journal Article

Exploring the cancer genome in the era of next-generation sequencing

Hui Dong, Shengyue Wang

Journal Article

Comparative study on microbial community in intermittently aerated sequencing batch reactors (SBR) and

Xiaolin Sheng, Rui Liu, Xiaoyan Song, Lujun Chen, Kawagishi Tomoki

Journal Article

Simultaneous denitrifying phosphorus accumulation in a sequencing batch reactor

YUAN Linjiang, HAN Wei, WANG Lei, YANG Yongzhe, WANG Zhiying

Journal Article

Improvement of nitrification efficiency by bioaugmentation in sequencing batch reactors at low temperature

Di CUI,Ang LI,Tian QIU,Rui CAI,Changlong PANG,Jihua WANG,Jixian YANG,Fang MA,Nanqi REN

Journal Article

Interplay between diet and genetic susceptibility in obesity and related traits

Tiange Wang, Min Xu, Yufang Bi, Guang Ning

Journal Article

Effects of La, Ce on nitrogen removal in sequencing batch reactor

Qing XIA , Rui LIANG , Yuning HONG , Lili DING , Hongqiang REN , Yuxiang MAO , Mingyu ZHAO ,

Journal Article

Optimal design of steel skeletal structures using the enhanced genetic algorithm methodology

Tugrul TALASLIOGLU

Journal Article

METAGENOMICS COMBINED WITH HIGH-THROUGHPUT SEQUENCING REVEALS THE METHANOGENIC POTENTIAL OF FRESH CORN

Journal Article

Research progress on genetic improvement of

Chuanping YANG

Journal Article